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2026 College Football Odds: Week 0 Predictions

Week 0 college football betting odds are in, with experts predicting USC to score seven or more touchdowns against San Jose State while taking the under in UNC's rematch with TCU.

The 2026 college football season kicks off with Week 0 matchups that have caught the attention of sports bettors. USC enters as a favorite against San Jose State, with analysts expecting the Trojans to score seven or more touchdowns after putting up 59+ points in their last two season openers against similar opponents. xsportfeed.quest

In other notable matchups, North Carolina faces TCU in a Dublin rematch with weather concerns and new quarterbacks leading experts to take the under 47.5 points. Meanwhile, NC State looks to keep things close against Virginia in a rematch of last year's 35-31 contest, with the Wolfpack favored to cover the spread with returning quarterback CJ Bailey.